Cenforce 150 mg (or any prescription sildenafil-based ED medication) involves multiple layers: 1. Regulatory Authorities In most countries, national drug regulatory agencies oversee the safety of approved medicines: U.S.: Food and Drug Administration (FDA) India: Central Drugs Standard Control Organization (CDSCO) EU: European Medicines Agency (EMA) These agencies track adverse events, require reporting from doctors and pharmaceutical companies, and can issue safety warnings, label updates, or recalls. 2. Pharmaceutical Manufacturers The company that produces Cenforce (e.g., Centurion Laboratories in India) must monitor, document, and report side effects as part of pharmacovigilance programs. They collect reports from doctors, pharmacists, and patients and submit them to the regulatory authorities. 3. Healthcare Professionals Doctors and pharmacists monitor patients who take Cenforce 150 mg. They are responsible for: Advising patients on possible side effects. Reporting adverse reactions to regulatory authorities or the manufacturer. Adjusting dosage or stopping the medicine if severe side effects occur. 4. Patients Patients themselves play a key role: Reporting any unexpected or severe side effects to their doctor or pharmacist. Reporting serious reactions to government programs (e.g., FDA MedWatch in the U.S.). Examples of common side effects that are monitored: headache, flushing, dizziness, nasal congestion, upset stomach. Serious side effects: priapism (erection >4 hours), vision or hearing changes, chest pain — these are urgent red flags that doctors report immediately.