Tazzle 20 mg may be better for you than sildenafil if you want a longer window of effectiveness, but neither medicine is universally better. Tazzle 20 mg contains tadalafil, while sildenafil is the active ingredient in medicines such as Manforce 100 mg. Both treat erectile dysfunction. European Association of Urology guidelines and medicine information. Uroweb +2 Which should you choose? For longer-lasting flexibility: tadalafil may be preferable. For planned ***** activity: sildenafil may suit you better. For stronger erections: neither is guaranteed to be stronger; the response varies by person. Important: Tazzle 20 mg is a high, on-demand tadalafil dose. A doctor may recommend starting at 10 mg instead. Do not combine tadalafil with sildenafil or take either with nitrate medicines, because of the risk of dangerously low blood pressure. 15293 +1 One question to help me guide you What matters most to you? A. Stronger, firmer erections B. Longer-lasting effects C. Fewer side effects D. Better performance with less anxiety