Super Vidalista, which contains both Tadalafil (the active ingredient in Vidalista) and Dapoxetine (a medication used to treat premature *****), is generally effective when taken with food. However, there are a few things to consider: Tadalafil (Vidalista component): Tadalafil can be taken with or without food, and food does not significantly affect its absorption or effectiveness. The main thing to keep in mind is that fatty meals may slightly delay the onset of action, but it doesn't make the medication less effective overall. Dapoxetine (Super Vidalista component): Dapoxetine, the selective serotonin reuptake inhibitor (SSRI) component used to treat premature *****, is usually taken with food or without food. It doesn't have strict food restrictions, but taking it with a meal may help to reduce any potential stomach discomfort. Key points: Effectiveness with food: The combination of Tadalafil and Dapoxetine in Super Vidalista is still effective if taken with food, but you may experience a slight delay in onset if you eat a large or fatty meal. Stomach comfort: Some people may find that taking Super Vidalista with food reduces potential stomach upset, though this is not a universal experience.