Kamagra Gold 100 mg contains sildenafil citrate, and sildenafil is metabolized primarily in the liver. Specifically: It is broken down mainly by the liver enzyme CYP3A4, with a smaller contribution from CYP2C9. After metabolism, the drug and its metabolites are eliminated mostly in the feces, with a smaller amount excreted in the urine. The elimination half-life of sildenafil is about 4 hours in healthy adults. Because the liver is responsible for most of its metabolism: People with moderate to severe liver impairment may have higher sildenafil levels in their blood and a greater risk of side effects. In those cases, healthcare providers often recommend a lower starting dose (such as 25 mg) rather than 100 mg. If your question is related to a liver condition or abnormal liver function tests, I can explain how that might affect the safety or dosing of sildenafil.