Organ transplantation for end stage organ failure can be a lifesaving intervention in patients with organ failure and mostly can be performed electively with few exceptions. Patients with acute liver failure, acute on chronic liver failure and those with hepatocellular cancer need an urgent transplant. Some countries have stopped living donor organ transplants (with exception for life saving measures) while some continue with deceased donor organ transplantation. However, due to risk of COVID-19 related morbidity and mortality in the recipient and living donor and cross infection of COVID-19 among other patients and health care workers (HCW), there is need for assessing overall the risk v/s benefit of organ transplantation. If in certain organs the risk of death is higher due to waiting then that patient should be considered for organ transplantation. As the situation improves, there may need to be a phased increment in transplantation services. It may be prudent to limit transplants to those who are struggling with non-transplant modalities of treatment.