Malegra FXT Plus can cause allergic reactions in some individuals. This medication combines 100 mg of sildenafil citrate (a PDE5 inhibitor) and 60 mg of fluoxetine (an SSRI), both of which can potentially trigger allergic responses. Reactions Allergic reactions to Malegra FXT Plus may include: Skin Rash: Red, itchy patches on the skin. Itching: Generalized or localized itching without a rash. Swelling: Particularly in the face, lips, tongue, or throat. Breathing Difficulties: Shortness of breath or wheezing. These reactions can vary in severity. In rare cases, they may progress to more serious conditions such as anaphylaxis, a severe, life-threatening allergic reaction. When to Seek Immediate Medical Attention If you experience any of the following symptoms after taking Malegra FXT Plus, seek emergency medical help immediately: Difficulty breathing or swallowing Swelling of the face, lips, tongue, or throat Severe dizziness or fainting Chest pain or irregular heartbeat These could indicate a serious allergic reaction or other severe side effects. Precautions Before Use Before starting Malegra FXT Plus, inform your healthcare provider if you have: A known allergy to sildenafil, fluoxetine, or any other components of the medication. A history of allergic reactions to other medications. Any cardiovascular issues, liver or kidney problems, or other significant health conditions. This information will help your doctor determine if Malegra FXT Plus is appropriate for you.