Cenforce (sildenafil) can interact with alcohol, mainly because both can lower blood pressure. Drinking alcohol while taking sildenafil may increase the chance of: Dizziness or light-headedness Headache and flushing Faster heartbeat A drop in blood pressure Difficulty getting or maintaining an erection, since heavy alcohol use itself can impair ***** performance A small amount of alcohol may not cause a serious problem for many people, but avoid heavy drinking, particularly if Cenforce already makes you dizzy or if you take blood-pressure medicines. Do not use Cenforce with nitrate medicines (such as nitroglycerin), regardless of alcohol consumption, because the combination can cause a dangerous blood-pressure drop. If you tell me your Cenforce dose and roughly how much alcohol you plan to drink, I can give you more specific guidance.