If Vidalista Professional contains tadalafil, it can sometimes be used long term, but the exact formulation and dose matter. Tadalafil has been studied in daily-use regimens, including patients treated for 1–2 years, with no new major safety signal identified in those studies. D DailyMed +1 However, I would not recommend taking Vidalista Professional continuously without medical supervision, particularly because products sold under that name can have different strengths/formulations. Long-term use needs extra caution if you: Take nitrates (nitroglycerin, isosorbide) — tadalafil should not be combined with them. Take certain alpha-blockers, blood-pressure medicines, or strong CYP3A4 inhibitors. Have significant heart, kidney, or liver disease. Develop persistent headaches, dizziness, low blood pressure, back/muscle pain, or other troublesome effects. D DailyMed +1 Emergency: an erection lasting more than 4 hours, sudden vision loss, sudden hearing loss, fainting, or severe chest pain requires urgent medical attention. D DailyMed If you tell me the strength and ingredients printed on your Vidalista Professional package (e.g., tadalafil 20 mg, or tadalafil + another ingredient), I can tell you whether that particular version is appropriate for long-term use and what dosing schedule is normally used.