If Poxet 60 mg contains dapoxetine 60 mg, it can be used safely in some men, but 60 mg is the maximum recommended dose and should not be the starting dose. According to current product information: Start with 30 mg, taken about 1–3 hours before ***** activity. If 30 mg is insufficient and you have no significant side effects such as dizziness, fainting, or other concerning reactions, a doctor may increase it to 60 mg. Take no more than one dose in 24 hours. N National Drug Formulary +1 The 60-mg dose has a higher incidence and severity of side effects, particularly dizziness and fainting. E European Medicines Agency (EMA) Avoid it if you have certain significant heart conditions, a history of fainting, moderate/severe liver disease, or take certain antidepressants or interacting medicines. N National Drug Formulary +1 Do not combine dapoxetine with PDE5 inhibitors such as sildenafil or tadalafil unless specifically directed by a clinician, because of potential effects on blood pressure and fainting risk. N National Drug Formulary Avoid alcohol, which can increase dizziness and fainting risk. S Safety and Quality in Health Care Bottom line: If you have never taken dapoxetine before, Poxet 30 mg is generally the appropriate starting strength rather than 60 mg. A 60-mg dose should be considered only after 30 mg has been tolerated and found insufficient. If you tell me your age, other medicines (especially Viagra/sildenafil or Cialis/tadalafil), and any heart or blood-pressure problems, I can explain whether 60 mg presents particular risks for you.