Malegra 100 mg is sildenafil 100 mg, you should discuss it with a doctor particularly if you: Have heart disease, chest pain, recent heart attack/stroke, or have been told ***** activity is unsafe for you. Take nitrate medicines such as nitroglycerin or isosorbide — sildenafil must not be combined with these. Take alpha-blockers or blood-pressure medicines, because sildenafil can lower blood pressure. Have significant kidney or liver problems; a lower starting dose may be appropriate. Take medicines that strongly affect sildenafil metabolism, such as ritonavir or certain antifungal/antibiotic medicines. Have previously had sudden vision or hearing loss, or conditions that increase the risk of prolonged erections. Even for otherwise healthy men, 100 mg is the maximum recommended sildenafil dose and should not be taken more than once a day. If you tell me your age, whether you take any regular medicines, and whether you have BP/heart/kidney/liver problems, I can tell you what specifically you should discuss with your doctor before taking Malegra 100.